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The use of minimally invasive techniques in cosmetology with the aim of increasing patient sensitivity

Most of the procedures in cosmetology are aimed at increasing the synthesis of new young collagen. In the article, Professor Yana Yutskovskaya offers new protocols and products to reduce the rehabilitation period in patients while maintaining high efficiency.
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Introduction
Modern medicine is taking more and more steps toward the “medicine of the future”, which, as you know, is based on the principles of 4P – predictive (precautionary), personalization (personification) and participatory (participatory), or adherence to treatment1.

Cosmetology, as one of the fastest growing areas of medicine, demonstrates the successful implementation of these principles. So, at the present stage, we are increasingly discussing the prevention of age-related skin changes rather than the fight against existing signs of aging. Patient surveys also show greater awareness and preparedness for prevention among the millennials. For example, an annual study by members of the American Academy of Facial Plastic and Reconstructive Surgery (AAFPRS) showed that 72% of facial plastic surgeons show an increase in interest in cosmetic procedures in patients under 30 years of age2.

This study also shows that modern young women and men are more interested in non-invasive and minimally invasive cosmetic procedures to prevent aging. And so it turns out that less traumatization of the skin guarantees greater patient sensitivity, which brings modern cosmetology even closer to the “medicine of the future”.

The goal of most cosmetology procedures aimed at combating skin aging is to increase the synthesis of new young collagen – neocollagenogenesis.

However, if we recall how and due to which transcutaneous induction of collagen synthesis occurs, it becomes clear that we still need trauma

It turns out that since we cannot exclude trauma, we should strive to minimize it so as not to reduce the patient sensitivity. Very often, we have to compensate for the relatively low level of injury by introducing hyaluronic acid and other components into the dermis, which in turn also has a number of limitations in the direction of participatory activity. Some patients are not ready for a long rehabilitation period, the presence of papules and hematomas.

All this motivates companies and specialists in aesthetic medicine to develop new protocols and products to reduce the rehabilitation period in patients while maintaining high efficiency.

An excellent example is the Perfoskin product from the developer and manufacturer of solutions in aesthetic medicine – Hyalual.

Benefits of Perfoskin over other products for skin quality:
rehabilitation period without papules and bruises due to sterile ultra-thin needles with laser sharpening and a length of 1.2 mm;
30 times more punctures (trauma → collagen synthesis induction) and three times less procedure duration due to a special delivery device;
the ability to work with two layers of the skin (dermis and epidermis) in three zones (face, neck, décolleté) in one procedure.
Perfoskin® Complex consists of Perfoskin® Device and Perfoskin® Prederm:
Perfoskin® Device – a device for transdermal delivery, allows for puncture and delivery of the drug simultaneously. It is a system of channels, holes and 48 ultra-thin needles with laser sharpening, 1.2 mm long, made of medical grade stainless steel for single use.
Perfoskin® Prederm is a 5 ml gel container containing 80 mg of hyaluronic acid-based sodium succinate.

Succinic acid, being a product of the tricarboxylic acid cycle, combines the properties of an active antioxidant and antihypoxant. Transferring energy metabolism to a more economical way, it helps preserve the skin’s energy reserves. Succinic acid normalizes the content of mediators of histamine and serotonin inflammation, increases microcirculation in organs and tissues without changing systemic hemodynamics. External succinate has a moderate antihypoxic effect, improving the acceptance of circulating oxygen and increasing resistance to hypoxia. In the process of succinate catabolism, other organic acids are utilized, which helps to restore acid-base balance and provides prevention of the development of inflammatory acidosis, for example, after excessive insolation. Influencing the Krebs cycle, it helps to reduce the formation of lactic and pyruvic acids, which appear in conditions of oxygen deficiency (hypoxia) 6,7,8. In addition, the introduction of one succinate was sufficient to obtain the entire pool of organic acids of the Krebs cycle. Numerous experiments have shown that the power of the energy production system using succinic acid as the main substrate is hundreds of times greater than other energy production systems in the body9.

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